United States securities and exchange commission logo July 22, 2022 Bryan Rowland General Counsel Vertex, Inc. 2301 Renaissance Blvd King of Prussia, Pennsylvania 19406 Re: Vertex, Inc. Registration Statement on Form S-3 Filed July 15, 2022 File No. 333-266168 Dear Mr. Rowland: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Priscilla Dao, Staff Attorney, at (202) 551-5997 or Joshua Shainess, Legal Branch Chief, at (202) 551-7951 with any questions. Sincerely, Division of Corporation Finance Office of Technology cc: William K. Hackett